You certainly can... You'll have to soup it up with a bunch of extensions and add-ons to get anywhere.

Most of the Sublime users I know have migrated to VS Code - which is a well known memory hog.

Sublime does have the benefit of being extremely fast and the ability to do multiple things in very large documents at speed. I keep it around for this reason. Every so often you wind up with a huge search and replace or regex that brings VS Code to its knees.